Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 17/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212075 | 0.88 | PTGER2 (0.59) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2212084 | 0.88 | PTGER2 (0.59) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3126929 | 0.87 | PTGER2 (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2213017 | 0.85 | PTGER2 (0.52) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2213022 | 0.85 | PTGER2 (0.52) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3123473 | 0.83 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3137332 | 0.83 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5953682 | 0.83 | PTGER2 (0.65) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5953685 | 0.83 | PTGER2 (0.65) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3136994 | 0.82 | PTGER4 (0.44) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613621-B1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA LTD (CA) | 2010-07-21 | — | — | EP | claimed |