Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983782 | 0.94 | KCNH2 (0.36) | PIK3CDSLC6A4HTR2CHTR2BHTR2A | |
| SCHEMBL31321973 | 0.88 | PIK3CD (0.39) | PIK3CDSLC6A4HTR2CHTR2BSLC6A2 | |
| SCHEMBL31269381 | 0.88 | PIK3CD (0.38) | PIK3CDHTR2CHTR2BKCNH2 | |
| SCHEMBL30983481 | 0.87 | KCNH2 (0.34) | PIK3CDKCNH2 | |
| SCHEMBL31268925 | 0.87 | KCNH2 (0.38) | PIK3CDKCNH2 | |
| SCHEMBL31268763 | 0.85 | KCNH2 (0.34) | PIK3CDKCNH2 | |
| SCHEMBL30983885 | 0.85 | CNR1 (0.33) | PIK3CDCNR1KCNH2 | |
| SCHEMBL31269351 | 0.85 | PIK3CD (0.35) | PIK3CDCNR1KCNH2 | |
| SCHEMBL31268765 | 0.85 | TLR7 (0.37) | PIK3CDCNR1KCNH2 | |
| SCHEMBL31269005 | 0.85 | PDE2A (0.35) | PIK3CDCNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |