Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983484 | 0.91 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL30983368 | 0.91 | PIK3CD (0.36) | PIK3CDDGAT1ACACBCNR1CNR2 | |
| SCHEMBL31268843 | 0.89 | GRM2 (0.38) | PIK3CDDGAT1CSF1RPIK3R1 | |
| SCHEMBL31269240 | 0.89 | PDE8A (0.35) | PIK3CDDGAT1ROCK2CNR1HCRTR1 | |
| SCHEMBL31269332 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269283 | 0.88 | PIK3CD (0.38) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31268788 | 0.87 | PIK3CD (0.37) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269110 | 0.87 | PIK3CD (0.38) | PIK3CDDGAT1ACACBCNR1CNR2 | |
| SCHEMBL31268991 | 0.87 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269290 | 0.86 | PIK3CD (0.37) | PIK3CDDGAT1ROCK2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |