Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983484 | 0.92 | PIK3CD (0.36) | PIK3CDDGAT1CNR1 | |
| SCHEMBL30983368 | 0.92 | PIK3CD (0.36) | PDE8APIK3CDDGAT1CNR1PDE10A | |
| SCHEMBL31269255 | 0.92 | PDE10A (0.38) | PLA2G2APIK3CDDGAT1CNR1PDE10A | |
| SCHEMBL31269316 | 0.91 | PIK3CD (0.35) | PLA2G2APIK3CDDGAT1CNR1PDE10A | |
| SCHEMBL31268757 | 0.90 | PLA2G2A (0.38) | PLA2G2A | |
| SCHEMBL31269332 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1CNR1 | |
| SCHEMBL31269347 | 0.89 | PIK3CD (0.34) | PIK3CDDGAT1CNR1ROCK2HCRTR1 | |
| SCHEMBL31269283 | 0.88 | PIK3CD (0.38) | PIK3CDDGAT1CNR1PDE10A | |
| SCHEMBL31268991 | 0.87 | PIK3CD (0.36) | PIK3CDDGAT1CNR1PDE10A | |
| SCHEMBL31269290 | 0.87 | PIK3CD (0.37) | PLA2G2APIK3CDDGAT1CNR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |