Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268997 | 0.85 | PIK3CD (0.35) | LRRK2CNR1PIK3CDKCNH2SCN5A | |
| SCHEMBL31268973 | 0.84 | PIK3CD (0.38) | CNR1CNR2PIK3CDKCNH2SCN5A | |
| SCHEMBL31269090 | 0.84 | HTR6 (0.35) | CNR1PIK3CDHTR6KCNH2SCN5A | |
| SCHEMBL31269023 | 0.84 | PIK3CD (0.35) | LRRK2CNR1PIK3CDKCNH2SCN5A | |
| SCHEMBL31269320 | 0.83 | HTR6 (0.34) | CNR1PIK3CDHTR6KCNH2SCN5A | |
| SCHEMBL31268739 | 0.83 | NOTUM (0.39) | CNR1CNR2PIK3CD | |
| SCHEMBL31268791 | 0.83 | CNR1 (0.39) | LRRK2CNR1CNR2PIK3CDKCNH2 | |
| SCHEMBL31269333 | 0.82 | PIK3CD (0.37) | CNR1CNR2PIK3CDKCNH2SCN5A | |
| SCHEMBL31269124 | 0.82 | CNR1 (0.33) | CNR1CNR2PIK3CDKCNH2SCN5A | |
| SCHEMBL30983779 | 0.81 | KCNH2 (0.36) | CNR1PIK3CDKCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |