Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269166 | 0.96 | ALDH1A1 (0.40) | ALDH1A1GBA1PIK3CDKMT2AMEN1 | |
| SCHEMBL31269015 | 0.94 | ALDH1A1 (0.32) | ALDH1A1GBA1PIK3CDKMT2AMEN1 | |
| SCHEMBL31268824 | 0.90 | PIK3CD (0.34) | ALDH1A1PIK3CDNPC1RAB9APKM | |
| SCHEMBL31269254 | 0.90 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL31269460 | 0.90 | PIK3CD (0.34) | PIK3CDNPC1RAB9A | |
| SCHEMBL31268842 | 0.90 | PIK3CD (0.33) | PIK3CDNPC1RAB9A | |
| SCHEMBL31269027 | 0.89 | PIK3CD (0.32) | PIK3CDNPC1RAB9A | |
| SCHEMBL31269392 | 0.89 | PIK3CD (0.34) | PIK3CDNPC1RAB9A | |
| SCHEMBL31268837 | 0.89 | KDM4E (0.33) | ALDH1A1PIK3CDKDM4ENPC1RAB9A | |
| SCHEMBL31268935 | 0.89 | PDE2A (0.34) | PIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |