Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31271114 | 0.91 | ALDH1A1 (0.52) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL31271238 | 0.91 | MEN1 (0.46) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL31270825 | 0.87 | NPC1 (0.51) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL31271184 | 0.85 | MEN1 (0.44) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL31270638 | 0.84 | BCHE (0.49) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL31270585 | 0.79 | MEN1 (0.44) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL11745274 | 0.78 | MEN1 (0.62) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL31270926 | 0.78 | NPC1 (0.46) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL31270851 | 0.76 | MEN1 (0.47) | MEN1KMT2ANFE2L2MAPTALDH1A1 | |
| SCHEMBL31270730 | 0.76 | MEN1 (0.47) | MEN1KMT2ANFE2L2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220035-A1 | THIOL-SPECIFIC SILICON-CONTAINING BIOCOMPATIBLE CLICK REAGENT: BETA-SILYL ALKYNYL CARBONYL COMPOUNDS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-10-24 | — | — | WO | disclosed |