Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | UBE2N | P61088 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL31271011 | 0.95 | PPARG (0.58) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL31270741 | 0.92 | NISCH (0.52) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL15615299 | 0.88 | ACHE (0.81) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL15788315 | 0.85 | PPARG (0.61) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL17086964 | 0.85 | ACHE (0.82) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL31270848 | 0.84 | PPARG (0.54) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL25604689 | 0.83 | ACHE (0.74) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL31270776 | 0.82 | NISCH (0.55) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL14679056 | 0.82 | ACHE (0.90) | NISCHACHEPPARGUBE2NPAX8 | |
| SCHEMBL25606799 | 0.81 | ACHE (0.70) | NISCHACHEPPARGUBE2NPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220676-A1 | MRNA DEGRADERS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |