SCHEMBL31273014

SCHEMBL31273014

C=Cc1ccc(Cn2nnc(C)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
TP53 P04637 2/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.42
RAB9A P51151 3/20 0.40
LMNA P02545 2/20 0.40
NPC1 O15118 2/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ALDH1A1 P00352 1/20 0.35
ENPP2 Q13822 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31272693 0.81 MAPT (0.41) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272414 0.81 RAB9A (0.58) MAPTKMT2ATP53MEN1RAB9A
SCHEMBL31272742 0.81 HDAC6 (0.45) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272431 0.81 POLB (0.42) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272318 0.81 POLB (0.42) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272684 0.81 POLB (0.42) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272097 0.81 POLB (0.42) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272223 0.80 MAPT (0.40) MAPTKMT2ATP53MEN1POLB
SCHEMBL31272213 0.80 MAPT (0.40) MAPTKMT2ATP53MEN1POLB
SCHEMBL21793669 0.80 KMT2A (0.55) MAPTKMT2AMEN1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed