Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | SNCA | P37840 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 4/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15380944 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL950792 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL950793 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL14455585 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL13973080 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL18646434 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL11860013 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL14532645 | 0.81 | CYP19A1 (0.69) | SHBGLMNAHSD17B10CYP19A1SERPINA6 | |
| SCHEMBL183701 | 0.81 | CYP19A1 (0.60) | CYP19A1 | |
| SCHEMBL9157360 | 0.79 | SHBG (0.66) | SHBGLMNAHSD17B10CYP19A1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018169-A2 | USE OF 4,17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | Teichmann, Alexander Tobias (DE) | 2009-01-28 | — | — | EP | claimed |
| WO-2007131736-A2 | USE OF 4, 17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | TEICHMANN ALEXANDER TOBIAS (DE) | 2007-11-22 | — | — | WO | claimed |
| EP-2018169-B1 | USE OF 4,17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | MABEL GMBH (DE) | 2010-11-10 | — | — | EP | disclosed |
| US-20100009927-A1 | Anti-Inflammatory and Anti-Allergy Extracts from Nettle | HERBALSCIENCE GROUP LLC (US) | 2010-01-14 | — | — | US | disclosed |
| WO-2009062683-A1 | C-19 STEROIDS FOR THERAPEUTIC USES | ERLACOS GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |
| EP-2018169-A2 | USE OF 4,17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | Teichmann, Alexander Tobias (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-2018169-A2 | USE OF 4,17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | Teichmann, Alexander Tobias (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-2018170-A2 | MEDICATION AGAINST BREAST CANCER AND RELATED DISEASES | Teichmann, Alexander Tobias (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-2005179-A2 | FLUORESCENCE BASED DETECTION OF SUBSTANCES | University of East Anglia (GB) | 2008-12-24 | — | — | EP | disclosed |
| US-20080075772-A1 | PHARMACEUTICAL COMPOSITIONS HAVING NOVEL SCORING PATTERNS AND METHODS OF USING THOSE COMPOSITIONS | ACCU-BREAK TECHNOLOGIES, INC. | 2008-03-27 | — | — | US | disclosed |
| WO-2007131736-A3 | USE OF 4, 17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | TEICHMANN ALEXANDER TOBIAS (DE) | 2008-03-06 | — | — | WO | disclosed |
| WO-2007131737-A2 | MEDICATION AGAINST BREAST CANCER AND RELATED DISEASES | TEICHMANN ALEXANDER TOBIAS (DE) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007131736-A2 | USE OF 4, 17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | TEICHMANN ALEXANDER TOBIAS (DE) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007131736-A2 | USE OF 4, 17 BETA-DIHYDROXYANDROST-4-ENE-3-ONE FOR TREATING CANCERS | TEICHMANN ALEXANDER TOBIAS (DE) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007110605-A2 | FLUORESCENCE BASED DETECTION OF SUBSTANCES | UNIVERSITY OF EAST ANGLIA (GB) | 2007-10-04 | — | — | WO | disclosed |
| EP-0759928-A1 | SYNTHESIS OF 17BETA-CYANO-3-ETHOXY-17ALPHA-HYDROXY-6-METHYLANDROSTA-3,5,9(11)-TRIENE | THE UPJOHN COMPANY (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995030684-A1 | SYNTHESIS OF 17β-CYANO-3-ETHOXY-17α-HYDROXY-6-METHYLANDROSTA-3,5,9(11)-TRIENE | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |
| US-5352809-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing such steroids | GIST-BROCADES N.V. (NL) | 1994-10-04 | — | — | US | disclosed |