SCHEMBL31274367

SCHEMBL31274367

CN1Cc2nn(C3CC3)nc2-c2cccc(N)c21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 1/20 0.33
HTR2B P41595 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29866564 0.82 TYK2 (0.37) TYK2
SCHEMBL25573062 0.82 TYK2 (0.37) TYK2
SCHEMBL30696887 0.81 TYK2 (0.33) TYK2
SCHEMBL26677529 0.81 TYK2 (0.33) TYK2
SCHEMBL31274096 0.79 KMT2A (0.35) TYK2
SCHEMBL29866375 0.77 TYK2 (0.44) TYK2
SCHEMBL26677510 0.75 TYK2 (0.33) TYK2
SCHEMBL29866220 0.75 TYK2 (0.38) TYK2
SCHEMBL27107327 0.73 TYK2 (0.32) TYK2
SCHEMBL29865894 0.73 PDE10A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720064-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2026-04-08 EP disclosed
WO-2024246602-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2024-12-05 WO disclosed