Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25573062 | 1.00 | TYK2 (0.37) | TYK2MAPTMAPK13EIF2AK2MAPK12 | |
| SCHEMBL29866220 | 0.92 | TYK2 (0.38) | TYK2 | |
| SCHEMBL29866375 | 0.92 | TYK2 (0.44) | TYK2 | |
| SCHEMBL29866515 | 0.85 | MAPT (0.31) | TYK2MAPTMAPK13EIF2AK2MAPK12 | |
| SCHEMBL26677698 | 0.83 | TYK2 (0.31) | TYK2 | |
| SCHEMBL31274367 | 0.82 | TYK2 (0.33) | TYK2 | |
| SCHEMBL27107221 | 0.79 | TYK2 (0.38) | TYK2MAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL29865894 | 0.79 | PDE10A (0.32) | — | |
| SCHEMBL29866374 | 0.78 | TYK2 (0.32) | TYK2MAPK14 | |
| SCHEMBL25573075 | 0.78 | TYK2 (0.32) | TYK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532485-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| WO-2024246599-A1 | CONDENSED AZINES AS TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |
| CN-117242072-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023227946-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-11-30 | — | — | WO | disclosed |
| WO-2022175747-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |