⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588183 | 1.00 | — | — | |
| SCHEMBL882973 | 1.00 | — | — | |
| SCHEMBL2034574 | 1.00 | — | — | |
| SCHEMBL5207176 | 1.00 | — | — | |
| SCHEMBL312745 | 1.00 | — | — | |
| SCHEMBL6079315 | 1.00 | — | — | |
| SCHEMBL2182805 | 1.00 | — | — | |
| SCHEMBL312743 | 1.00 | — | — | |
| SCHEMBL7558402 | 0.98 | SLC1A2 (0.56) | — | |
| SCHEMBL7558398 | 0.98 | SLC1A2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2190 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11203622-B2 | MASP isoforms as inhibitors of complement activation | OMEROS CORPORATION (US) | 2021-12-21 | — | — | US | claimed |
| EP-2688578-B1 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR PREVENTING AND CURING VITILIGO | BORDIGNON MATTEO (IT) | 2019-03-27 | — | — | EP | claimed |
| CN-103930122-A | MIA (melanoma inhibitory activity protein) inhibitor for detecting, preventing and treating leukoderma | BORDIGNON MATTEO | 2014-07-16 | — | — | CN | claimed |
| US-20140155371-A1 | MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE | BASF SE (DE) | 2014-06-05 | — | — | US | claimed |
| EP-2688578-A2 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR DETECTING, PREVENTING AND CURING VITILIGO | Bordignon, Matteo (IT) | 2014-01-29 | — | — | EP | claimed |
| US-20140004130-A1 | MIA (Melanoma Inhibitory Activity) Inhibitors for Detecting, Preventing and Curing Vitiligo | BORDIGNON MATTEO (IT) | 2014-01-02 | — | — | US | claimed |
| WO-2013014604-A1 | MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE | BASF SE (DE) | 2013-01-31 | — | — | WO | claimed |
| WO-2012127352-A2 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR DETECTING, PREVENTING AND CURING VITILIGO | BORDIGNON MATTEO (IT) | 2012-09-27 | — | — | WO | claimed |
| US-20120208774-A1 | METHOD FOR INHIBITING \"MELANOMA INHIBITORY ACTIVITY\" MIA | ANTISENSE PHARMA GMBH (DE) | 2012-08-16 | — | — | US | claimed |
| US-8148493-B2 | Method for inhibiting “melanoma inhibitory activity” MIA | ANTISENSE PHARMA GMBH (DE) | 2012-04-03 | — | — | US | claimed |
| US-20100273705-A1 | Method for inhibiting \"Melanoma Inhibitory Activity\" MIA | ANTISENSE PHARMA GMBH. | 2010-10-28 | — | — | US | claimed |
| US-20090148921-A1 | Compositions and methods for enhancing apoptosis | GENENTECH, INC. (US) | 2009-06-11 | — | — | US | claimed |
| EP-1590666-B1 | COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS | GENENTECH INC (US) | 2008-07-09 | — | — | EP | claimed |
| US-20060128607-A1 | Method for inhibiting \"melanoma inhibitory activity\" mia | ANTISENSE PHARMA GMBH (DE) | 2006-06-15 | — | — | US | claimed |
| EP-1472279-A1 | A METHOD FOR INHIBITING \"MELANOMA INHIBITORY ACTIVITY\" MIA | Antisense Pharma GmbH (DE) | 2004-11-03 | — | — | EP | claimed |
| US-20040171554-A1 | Compositions and methods for enhancing apoptosis | GENENTECH, INC. | 2004-09-02 | — | — | US | claimed |
| WO-2003064457-A1 | A METHOD FOR INHIBITING 'MELANOMA INHIBITORY ACTIVITY' MIA | ANTISENSE PHARMA GMBH (DE) | 2003-08-07 | — | — | WO | claimed |
| US-20260146104-A1 | ANTIBODIES, ACTIVATABLE ANTIBODIES, BISPECIFIC ANTIBODIES, AND BISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF | CYTOMX THERAPEUTICS, INC. (US) | 2026-05-28 | — | — | US | disclosed |
| EP-0001845-A2 | Analeptic tripeptides, process for their preparation and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| US-4030994-A | FLUOROXY PENTAFLUOROSULFUR | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |