⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588183 | 1.00 | — | — | |
| SCHEMBL882973 | 1.00 | — | — | |
| SCHEMBL2034574 | 1.00 | — | — | |
| SCHEMBL5207176 | 1.00 | — | — | |
| SCHEMBL312744 | 1.00 | — | — | |
| SCHEMBL6079315 | 1.00 | — | — | |
| SCHEMBL2182805 | 1.00 | — | — | |
| SCHEMBL312743 | 1.00 | — | — | |
| SCHEMBL7558402 | 0.98 | SLC1A2 (0.56) | — | |
| SCHEMBL7558398 | 0.98 | SLC1A2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2552 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085272-A | Isaridin cyclic depsipeptide derivative and preparation method and application thereof | 中山大学 | 2022-02-25 | — | — | CN | claimed |
| US-11203622-B2 | MASP isoforms as inhibitors of complement activation | OMEROS CORPORATION (US) | 2021-12-21 | — | — | US | claimed |
| EP-2688578-B1 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR PREVENTING AND CURING VITILIGO | BORDIGNON MATTEO (IT) | 2019-03-27 | — | — | EP | claimed |
| US-8912146-B2 | Derivatives of APF and methods of use | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-12-16 | — | — | US | claimed |
| CN-103930122-A | MIA (melanoma inhibitory activity protein) inhibitor for detecting, preventing and treating leukoderma | BORDIGNON MATTEO | 2014-07-16 | — | — | CN | claimed |
| US-20140155371-A1 | MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE | BASF SE (DE) | 2014-06-05 | — | — | US | claimed |
| EP-2688578-A2 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR DETECTING, PREVENTING AND CURING VITILIGO | Bordignon, Matteo (IT) | 2014-01-29 | — | — | EP | claimed |
| US-20140004130-A1 | MIA (Melanoma Inhibitory Activity) Inhibitors for Detecting, Preventing and Curing Vitiligo | BORDIGNON MATTEO (IT) | 2014-01-02 | — | — | US | claimed |
| WO-2013014604-A1 | MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE | BASF SE (DE) | 2013-01-31 | — | — | WO | claimed |
| WO-2012127352-A2 | MIA (MELANOMA INHIBITORY ACTIVITY) INHIBITORS FOR DETECTING, PREVENTING AND CURING VITILIGO | BORDIGNON MATTEO (IT) | 2012-09-27 | — | — | WO | claimed |
| US-8148493-B2 | Method for inhibiting “melanoma inhibitory activity” MIA | ANTISENSE PHARMA GMBH (DE) | 2012-04-03 | — | — | US | claimed |
| WO-2011085393-A1 | STABLE INSULIN FORMULATIONS AND METHODS OF MAKING AND USING THEREOF | GENECOPOEIA, INC. (US) | 2011-07-14 | — | — | WO | claimed |
| US-20100273705-A1 | Method for inhibiting \"Melanoma Inhibitory Activity\" MIA | ANTISENSE PHARMA GMBH. | 2010-10-28 | — | — | US | claimed |
| US-20060128607-A1 | Method for inhibiting \"melanoma inhibitory activity\" mia | ANTISENSE PHARMA GMBH (DE) | 2006-06-15 | — | — | US | claimed |
| EP-1472279-A1 | A METHOD FOR INHIBITING \"MELANOMA INHIBITORY ACTIVITY\" MIA | Antisense Pharma GmbH (DE) | 2004-11-03 | — | — | EP | claimed |
| WO-2003064457-A1 | A METHOD FOR INHIBITING 'MELANOMA INHIBITORY ACTIVITY' MIA | ANTISENSE PHARMA GMBH (DE) | 2003-08-07 | — | — | WO | claimed |
| US-6084065-A | FOR AGRICULTURAL USE | ISAGRO SPA (IT) | 2000-07-04 | — | — | US | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| EP-0718280-A2 | Derivatives of beta-aminopropionic acid with a fungicidal activity | ISAGRO RICERCA S.r.l. (IT) | 1996-06-26 | — | — | EP | claimed |
| EP-0652229-A2 | Oligopeptides with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-05-10 | — | — | EP | claimed |