Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115808 | 1.00 | ATR (0.41) | ATRMETAP1CYP17A1SREBF2CA1 | |
| SCHEMBL26542469 | 0.81 | ATR (0.35) | ATRMETAP1CYP17A1SREBF2CA1 | |
| SCHEMBL26115978 | 0.79 | HDAC3 (0.36) | — | |
| SCHEMBL1697945 | 0.79 | METAP1 (0.39) | ATRMETAP1CYP17A1CA1CA2 | |
| SCHEMBL1100453 | 0.78 | METAP1 (0.47) | ATRMETAP1CYP17A1LCKPSMB8 | |
| SCHEMBL26118724 | 0.76 | ATR (0.51) | ATRMETAP1CYP17A1SREBF2CA1 | |
| SCHEMBL30587238 | 0.76 | ATR (0.51) | ATRMETAP1CYP17A1SREBF2CA1 | |
| SCHEMBL29544697 | 0.72 | GSK3B (0.44) | ATRCYP17A1SREBF2MAP4K4NAMPT | |
| SCHEMBL27458270 | 0.70 | SYK (0.42) | ATRCYP17A1SREBF2CA1CA12 | |
| SCHEMBL13367308 | 0.69 | METAP1 (0.46) | ATRMETAP1CA1LCKCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095853-A | KRAS inhibitors | 伊莱利利公司 | 2024-12-06 | — | — | CN | disclosed |