Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.67 |
| ▸ | RAB9A | P51151 | 12/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | SCD | O00767 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3357182 | 0.97 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL8280120 | 0.87 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL31061590 | 0.80 | DYRK1A (1.00) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL2895657 | 0.78 | SMN1; SMN2 (0.67) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL11850147 | 0.77 | DYRK1A (0.64) | NPC1RAB9ASMN1; SMN2DYRK1ATP53 | |
| SCHEMBL2400142 | 0.77 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL95067 | 0.77 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL31276816 | 0.77 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL13390826 | 0.77 | ATAD2 (0.81) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL3408807 | 0.76 | IDO1 (0.70) | NPC1RAB9ASMN1; SMN2DYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |
| US-3967950-A | Combating weeds in rice with benzothiazole derivatives | NIPPON SODA COMPANY LIMITED (JA) | 1976-07-06 | — | — | US | disclosed |