Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526682 | 0.92 | DDB1 (0.55) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL31160731 | 0.92 | DDB1 (0.55) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL23540784 | 0.92 | DDB1 (0.55) | DDB1CRBNKDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL30258269 | 0.91 | DDB1 (0.54) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL31323431 | 0.89 | DDB1 (0.54) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL31068575 | 0.88 | DDB1 (0.52) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL31281910 | 0.88 | DDB1 (0.53) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL29579240 | 0.88 | DDB1 (0.51) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL24480442 | 0.88 | DDB1 (0.51) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL24607783 | 0.87 | DDB1 (0.52) | DDB1CRBNKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731309-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025076044-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | PAQ Therapeutics Inc. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2024263586-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | PAQ Therapeutics Inc. (US) | 2024-12-26 | — | — | WO | disclosed |