Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.48 |
| ▸ | YAP1 | P46937 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706089 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL18921640 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL23249942 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL29132053 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL27242967 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL30942476 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL26925218 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL14716132 | 0.83 | ENPP2 (0.56) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL2440617 | 0.83 | ENPP2 (0.56) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL25308718 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731309-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024263586-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | PAQ Therapeutics Inc. (US) | 2024-12-26 | — | — | WO | disclosed |