Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31282557 | 0.93 | DRD2 (0.36) | DRD2SLC6A4CYP3A4OPRM1DDB1 | |
| SCHEMBL31282708 | 0.90 | DRD2 (0.42) | DRD2SLC6A4CYP3A4OPRM1DDB1 | |
| SCHEMBL31281914 | 0.89 | DRD2 (0.38) | DRD2SLC6A4CYP3A4OPRM1DDB1 | |
| SCHEMBL31282093 | 0.89 | DRD2 (0.38) | DRD2SLC6A4CYP3A4OPRM1DDB1 | |
| SCHEMBL31282427 | 0.88 | DRD2 (0.41) | DRD2SLC6A4CYP3A4DDB1CRBN | |
| SCHEMBL31281909 | 0.88 | DRD2 (0.41) | DRD2SLC6A4CYP3A4OPRM1DDB1 | |
| SCHEMBL31282081 | 0.87 | DRD2 (0.44) | DRD2SLC6A4CYP3A4OPRM1DDB1 | |
| SCHEMBL31281965 | 0.87 | DRD2 (0.39) | DRD2SLC6A4CYP3A4DDB1CRBN | |
| SCHEMBL29172730 | 0.84 | KHK (0.36) | DRD2SLC6A4OPRM1OPRL1 | |
| SCHEMBL31281895 | 0.83 | DRD2 (0.35) | DRD2SLC6A4CYP3A4DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731309-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024263586-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | PAQ Therapeutics Inc. (US) | 2024-12-26 | — | — | WO | disclosed |