Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | GALR2 | O43603 | 3/20 | 0.44 |
| ▸ | GALR1 | P47211 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KHK | P50053 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130094 | 0.89 | POLB (0.58) | SRCALDH1A1KMT2AHTR2AKHK | |
| SCHEMBL3131779 | 0.88 | SRC (0.69) | SRCLMNAHTR2APOLB | |
| SCHEMBL3120081 | 0.82 | CDK1 (0.43) | NPSR1SRCLMNATAAR1GAA | |
| SCHEMBL13303605 | 0.78 | SYK (0.61) | SRC | |
| SCHEMBL30677276 | 0.77 | SRC (0.56) | SRCLMNAHTR2AHTR2C | |
| SCHEMBL3131464 | 0.76 | ROCK2 (0.46) | SRCKMT2AHTR2CKHKPOLB | |
| SCHEMBL459413 | 0.75 | IGF1R (0.51) | SRCGAAKMT2AMAPTADORA3 | |
| SCHEMBL3642979 | 0.74 | HRH4 (0.75) | NPSR1LMNAALDH1A1GAAKMT2A | |
| SCHEMBL183094 | 0.74 | POLB (0.57) | NPSR1LMNAALDH1A1GAAKMT2A | |
| SCHEMBL16146743 | 0.74 | CDK2 (0.40) | NPSR1SRCLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | NPSR1 2829/4885SRC 1007/4885LMNA 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.