Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 19/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007976 | 0.92 | MLNR (1.00) | MLNRCYP3A4CHRM4 | |
| SCHEMBL2009345 | 0.91 | MLNR (1.00) | MLNR | |
| SCHEMBL2008839 | 0.85 | MLNR (0.85) | MLNRCYP3A4 | |
| SCHEMBL3138321 | 0.84 | MLNR (0.72) | MLNR | |
| SCHEMBL2009415 | 0.83 | MLNR (1.00) | MLNRCYP3A4CHRM4 | |
| SCHEMBL4690685 | 0.83 | MLNR (1.00) | MLNRCYP3A4CHRM4 | |
| SCHEMBL2007837 | 0.82 | MLNR (0.73) | MLNRCYP3A4 | |
| SCHEMBL2012437 | 0.81 | MLNR (1.00) | MLNRCYP3A4 | |
| SCHEMBL2004322 | 0.77 | MLNR (1.00) | MLNRCYP3A4 | |
| Hydrochloric Acid SCHEMBL2009168 | 0.76 | MLNR (0.98) | MLNRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960390-B1 | BIARYL COMPOUNDS USEFUL AS AGONISTS OF THE GPR38 RECEPTOR | GLAXO GROUP LTD (GB) | 2010-07-21 | — | — | EP | claimed |