Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25389466 | 0.84 | HTR2C (0.54) | HTR2AHTR2CHTR2BHRH3CHRNB2 | |
| SCHEMBL25389269 | 0.84 | HTR2C (0.54) | HTR2AHTR2CHTR2BHRH3CHRNB2 | |
| SCHEMBL1239743 | 0.84 | HTR2A (0.52) | HTR2AHTR2CHTR2BHRH3HTR3A | |
| SCHEMBL31288411 | 0.79 | CHRNB2 (0.42) | HTR2AHTR2CHTR2BCHRNB2CHRNB4 | |
| SCHEMBL31288324 | 0.79 | CHRNB2 (0.42) | HTR2AHTR2CHTR2BCHRNB2CHRNB4 | |
| SCHEMBL25391366 | 0.79 | CHRNB2 (0.42) | HTR2AHTR2CHTR2BCHRNB2CHRNB4 | |
| SCHEMBL25390533 | 0.79 | CHRNB2 (0.42) | HTR2AHTR2CHTR2BCHRNB2CHRNB4 | |
| SCHEMBL25388873 | 0.77 | HRH3 (0.45) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL25389966 | 0.77 | HRH3 (0.45) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL25387605 | 0.77 | HRH3 (0.45) | HTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472963-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | Arvinas Operations, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118946556-A | DGK targeting compounds and uses thereof | 阿维纳斯运营公司 | 2024-11-12 | — | — | CN | disclosed |