Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454933 | 1.00 | ABL1 (0.46) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL24454936 | 0.87 | MAP4K4 (0.42) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL31285125 | 0.87 | MAP4K4 (0.42) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL26258668 | 0.83 | ALDH1A1 (0.59) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL31284754 | 0.83 | ALDH1A1 (0.59) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL24454900 | 0.78 | MAPK10 (0.44) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL24454920 | 0.78 | NPC1 (0.58) | MAP4K4NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL24454876 | 0.78 | MAPK10 (0.51) | ABL1MAP4K4NPC1RAB9AALDH1A1 | |
| SCHEMBL24454897 | 0.76 | KDM4E (0.69) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL25389382 | 0.76 | FASN (0.49) | ABL1MAP4K4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | claimed |