SCHEMBL3128571

SCHEMBL3128571

Clc1ccc(Cc2ccccn2)cc1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.65
KDM4E B2RXH2 2/20 0.55
TSHR P16473 1/20 0.55
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
CXCR3 P49682 1/20 0.52
SMN1; SMN2 Q16637 5/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
HSP90AB1 P08238 1/20 0.44
MAPT P10636 1/20 0.44
CNR1 P21554 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30271022 1.00 L3MBTL1 (0.65) L3MBTL1KDM4ETSHRNPC1RAB9A
SCHEMBL28341570 1.00 L3MBTL1 (0.65) L3MBTL1KDM4ETSHRNPC1RAB9A
Toluene SCHEMBL28430347 0.90 L3MBTL1 (0.54) L3MBTL1KDM4ETSHRNPC1RAB9A
SCHEMBL28172226 0.84 L3MBTL1 (0.65) L3MBTL1KDM4ETSHRCXCR3SMN1; SMN2
SCHEMBL29373231 0.83 L3MBTL1 (0.68) L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL64435 0.83 L3MBTL1 (0.68) L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL9253903 0.82 KDM4E (0.62) KDM4ETSHRNPC1RAB9ASMN1; SMN2
Bromide SCHEMBL10759788 0.81 L3MBTL1 (0.66) L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31276017 0.81 L3MBTL1 (0.66) L3MBTL1NPC1RAB9AALDH1A1
SCHEMBL31236458 0.81 L3MBTL1 (0.66) L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118931442-A Modified phenolic resin adhesive and preparation method thereof 江苏新冠制动科技有限公司 2024-11-12 CN claimed
CN-117924159-A Synthesis process of chlorpheniramine maleate 台州市源众药业有限公司 2024-04-26 CN claimed
CN-117624032-A Synthesis method of novel chlorpheniramine maleate 河南九势制药股份有限公司 2024-03-01 CN claimed
CN-110372578-A A kind of new chlorphenamine maleate synthetic method 嘉实(湖南)医药科技有限公司 2019-10-25 CN claimed
CN-106032355-B A kind of method that pyridine side chain c h bond is direct oxidation into ketone 中国科学院大连化学物理研究所 2019-01-04 CN claimed
CN-105669548-B A kind of method of manganese compound catalysis oxidation pyridine compounds and their synthesis ketone 中国科学院大连化学物理研究所 2018-04-03 CN claimed
CN-106883167-A A kind of new chlorphenamine maleate synthetic method 张燕梅 2017-06-23 CN claimed
CN-106032355-A Method for directly oxidizing C-H bond in side chain of pyridine into ketone 中国科学院大连化学物理研究所 2016-10-19 CN claimed
CN-105669548-A Ketone or aldehyde synthetic method by using manganese compound to conduct catalytic oxidation of pyridine compound 中国科学院大连化学物理研究所 2016-06-15 CN claimed
CN-105237469-A Preparation method of 4-chlorophenyl-2-pyridyl methanol HANGZHOU AOYIPOLLEN PHARMACEUTICAL CO LTD 2016-01-13 CN claimed
CN-101967120-A Preparation method of 2-p-chlorobenzyl pyridine UNIV GUANGXI 2011-02-09 CN claimed
CN-120247778-A Chlorpheniramine maleate method for separating intermediate impurities 台州市源众药业有限公司 2025-07-04 CN disclosed
CN-118931442-A Modified phenolic resin adhesive and preparation method thereof 江苏新冠制动科技有限公司 2024-11-12 CN disclosed
CN-117924159-A Synthesis process of chlorpheniramine maleate 台州市源众药业有限公司 2024-04-26 CN disclosed
CN-117924159-A Synthesis process of chlorpheniramine maleate 台州市源众药业有限公司 2024-04-26 CN disclosed
EP-0349358-A1 Process for presulfiding and controlling the activity of a hydrocarbon treatment catalyst EURECAT EUROPEENNE DE RETRAITEMENT DE CATALYSEURS (FR) 1990-01-03 EP disclosed
EP-0308328-A1 (Benzyl-piperidino)-1-propanol-2 derivatives, their preparation, their use as microbicides and compositions containing them SANOFI (FR) 1989-03-22 EP disclosed
US-4043790-A 2-OR 4-SUBSTITUTED PYRIDINE METHANE OR PYRIDINE METHANOL, NONHERBICIDAL ELI LILLY AND COMPANY (US) 1977-08-23 US disclosed
US-4026936-A Anthelmintic pyridine and thiazole substituted benzimidazole carbamates HOFFMANN-LA ROCHE INC. (US) 1977-05-31 US disclosed
US-3940386-A Substituted cinnamoyl-piperazine-pyridyl compound CERMOL S.A. 1976-02-24 US disclosed