Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23771028 | 0.83 | HTT (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31286944 | 0.79 | KDM4E (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL12011569 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL25989633 | 0.78 | KDM4E (0.52) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30523108 | 0.78 | KDM4E (0.52) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5342000 | 0.78 | SMN1; SMN2 (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1502539 | 0.78 | NAMPT (0.48) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL4167659 | 0.77 | HPGD (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1559057 | 0.76 | HTT (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31287149 | 0.76 | HPGD (0.68) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025022093-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2025-01-30 | — | — | WO | disclosed |