Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544560 | 0.77 | MAPT (0.55) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL5293345 | 0.77 | SMN1; SMN2 (0.63) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL31583966 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL24461541 | 0.76 | POLB (0.43) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL8880347 | 0.76 | MAPT (0.52) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL15919469 | 0.76 | MAPT (0.60) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL13363878 | 0.76 | CYP46A1 (0.49) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL13363888 | 0.75 | CYP19A1 (0.51) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL30516592 | 0.75 | CYP19A1 (0.51) | MAPTSMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL17652591 | 0.75 | MAPT (0.60) | MAPTSMN1; SMN2RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025022093-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2025-01-30 | — | — | WO | disclosed |