Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719666 | 1.00 | EPHX1 (0.34) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28716310 | 1.00 | EPHX1 (0.34) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6102995 | 0.91 | — | — | |
| SCHEMBL9412302 | 0.82 | — | — | |
| SCHEMBL28707168 | 0.81 | EPHX1 (0.33) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9020413 | 0.78 | EPHX1 (0.37) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8820682 | 0.77 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL5160612 | 0.76 | — | — | |
| SCHEMBL5456 | 0.76 | — | — | |
| SCHEMBL28615639 | 0.75 | POLB (0.38) | EPHX1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462659-A | Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113874079-B | Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof | 吉利德科学公司 | 2024-11-08 | — | — | CN | disclosed |