⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719666 | 0.91 | EPHX1 (0.34) | — | |
| SCHEMBL28716310 | 0.91 | EPHX1 (0.34) | — | |
| SCHEMBL31287285 | 0.91 | EPHX1 (0.34) | — | |
| SCHEMBL9412302 | 0.86 | — | — | |
| SCHEMBL8183728 | 0.79 | — | — | |
| SCHEMBL1302634 | 0.76 | — | — | |
| SCHEMBL1264064 | 0.76 | — | — | |
| SCHEMBL4388566 | 0.76 | — | — | |
| SCHEMBL28707168 | 0.71 | EPHX1 (0.33) | — | |
| SCHEMBL5160612 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683770-A1 | SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES | BAYER AG (DE) | 1995-11-29 | — | — | EP | claimed |
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | claimed |
| WO-1994018174-A1 | SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-18 | — | — | WO | claimed |
| US-5248689-A | Hypotensive agents, congestive heart failure, renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-28 | — | — | US | claimed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | claimed |
| US-20060128718-A1 | Tetrahydropyridazine derivatives having a pesticidal effect | BAYER CROPSCIENCE AG (DE) | 2006-06-15 | — | — | US | disclosed |
| US-20050150764-A1 | Tetrahydropyridazine derivatives and their use as pesticides | MAURER FRITZ (DE) | 2005-07-14 | — | — | US | disclosed |
| EP-1537101-A1 | TETRAHYDROPYRIDAZINE DERIVATIVES HAVING A PESTICIDAL EFFECT | Bayer CropScience Aktiengesellschaft (DE) | 2005-06-08 | — | — | EP | disclosed |
| EP-1414815-A1 | TETRAHYDROPYRIDAZINE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2004024722-A1 | TETRAHYDROPYRIDAZINE DERIVATIVES HAVING A PESTICIDAL EFFECT | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | WO | disclosed |
| WO-2003010162-A1 | TETRAHYDROPYRIDAZINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-02-06 | — | — | WO | disclosed |
| EP-0683770-A1 | SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| EP-0683770-A1 | SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994018174-A1 | SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-18 | — | — | WO | disclosed |
| WO-1994018174-A1 | SUBSTITUTED TETRAHYDROPYRIDAZINE CARBOXAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-18 | — | — | WO | disclosed |
| US-5248689-A | Hypotensive agents, congestive heart failure, renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |