Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefpodoxime. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.87 |
| ▸ | MAPT | P10636 | 5/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.87 |
| ▸ | APEX1 | P27695 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.87 |
| ▸ | POLB | P06746 | 2/20 | 0.87 |
| ▸ | RECQL | P46063 | 2/20 | 0.87 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.87 |
| ▸ | PKM | P14618 | 1/20 | 0.87 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.87 |
| ▸ | LMNA | P02545 | 1/20 | 0.87 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.87 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.87 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.85 |
| ▸ | HTR2C | P28335 | 1/20 | 0.85 |
| ▸ | ESR1 | P03372 | 2/20 | 0.77 |
| ▸ | DRD2 | P14416 | 1/20 | 0.77 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.77 |
| ▸ | PPARG | P37231 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefpodoxime SCHEMBL10740528 | 1.00 | TDP1 (0.87) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefpodoxime SCHEMBL10740505 | 1.00 | TDP1 (0.87) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| SCHEMBL9076385 | 0.93 | TDP1 (0.89) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefotaxime SCHEMBL41092 | 0.93 | TDP1 (1.00) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefotaxime SCHEMBL10569095 | 0.93 | TDP1 (1.00) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| SCHEMBL10738911 | 0.93 | TDP1 (0.76) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefotaxime SCHEMBL10486930 | 0.93 | TDP1 (1.00) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefotaxime SCHEMBL10486935 | 0.93 | TDP1 (1.00) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefotaxime SCHEMBL537163 | 0.93 | TDP1 (1.00) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Cefotaxime SCHEMBL9491367 | 0.93 | TDP1 (1.00) | TDP1MAPTHSD17B10APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120309632-A | Preparation method of cefpodoxime proxetil | 成都倍特药业股份有限公司 | 2025-07-15 | — | — | CN | disclosed |
| CN-118852204-A | Purification method of cefpodoxime proxetil | 艾美科健（中国）生物医药有限公司 | 2024-10-29 | — | — | CN | disclosed |