Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.76 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | RECQL | P46063 | 2/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128780 | 1.00 | PIK3CG (0.76) | PIK3CGDUSP3POLBALDH1A1MAPT | |
| SCHEMBL12004076 | 1.00 | PIK3CG (0.76) | PIK3CGDUSP3POLBALDH1A1MAPT | |
| SCHEMBL1064036 | 0.86 | PIK3CG (1.00) | PIK3CGPOLBMEN1KMT2ATDP1 | |
| SCHEMBL4200323 | 0.86 | PIK3CG (1.00) | PIK3CGPOLBMEN1KMT2ATDP1 | |
| SCHEMBL1064039 | 0.86 | PIK3CG (1.00) | PIK3CGPOLBMEN1KMT2ATDP1 | |
| SCHEMBL1082136 | 0.84 | PIK3CG (0.95) | PIK3CGPOLBMEN1KMT2AIGF1R | |
| SCHEMBL1082135 | 0.84 | PIK3CG (0.95) | PIK3CGPOLBMEN1KMT2AIGF1R | |
| SCHEMBL3125785 | 0.82 | PIK3CG (0.78) | PIK3CGPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL3366587 | 0.82 | PIK3CG (0.78) | PIK3CGPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL3125789 | 0.82 | PIK3CG (0.78) | PIK3CGPOLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | claimed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | claimed |
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | PIK3CG 4355/4885DUSP3 3629/4885POLB 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.