Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128820 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AL3MBTL1APP | |
| SCHEMBL3128813 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AL3MBTL1APP | |
| SCHEMBL3134661 | 0.82 | MAPT (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL3134656 | 0.82 | MAPT (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL31512479 | 0.75 | L3MBTL1 (0.60) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL3363287 | 0.74 | MEN1 (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL3125942 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1APP | |
| SCHEMBL3131528 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1APP | |
| SCHEMBL3125934 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1APP | |
| SCHEMBL29235063 | 0.73 | TSHR (0.55) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936211-B1 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | GIVAUDAN SA (CH) | 2010-07-07 | — | — | EP | claimed |
| EP-0936211-B1 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | GIVAUDAN SA (CH) | 2010-07-07 | — | — | EP | disclosed |
| US-6096918-A | USEFUL FOR THE DELIVERY OF ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES, MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS. THEY CAN ALSO DELIVER FLUORESCENT WHITENING AGENTS. | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2000-08-01 | — | — | US | disclosed |
| EP-0936211-A2 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 1999-08-18 | — | — | EP | disclosed |