Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135075 | 1.00 | HDAC1 (0.55) | HDAC1HDAC2GPR119NR1H2LIPE | |
| SCHEMBL31288417 | 1.00 | HDAC1 (0.55) | HDAC1HDAC2GPR119NR1H2LIPE | |
| SCHEMBL27399965 | 0.87 | GPR119 (0.67) | GPR119NR1H2LIPEALDH1A1LMNA | |
| SCHEMBL20511076 | 0.87 | GPR119 (0.67) | GPR119NR1H2LIPEALDH1A1LMNA | |
| SCHEMBL19078501 | 0.86 | GPR119 (0.50) | HDAC1HDAC2GPR119NR1H2LIPE | |
| SCHEMBL22523841 | 0.86 | GPR119 (0.52) | HDAC1HDAC2GPR119NR1H2LIPE | |
| SCHEMBL22015318 | 0.86 | GPR119 (0.52) | GPR119NR1H2LIPEALDH1A1LMNA | |
| SCHEMBL927555 | 0.86 | GPR119 (0.52) | GPR119NR1H2LIPEALDH1A1LMNA | |
| SCHEMBL29723219 | 0.86 | GPR119 (0.52) | HDAC1HDAC2GPR119NR1H2LIPE | |
| SCHEMBL12005457 | 0.86 | GPR119 (0.52) | HDAC1HDAC2GPR119NR1H2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472963-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | Arvinas Operations, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |