SCHEMBL31290142

SCHEMBL31290142

Cc1ccc(C)c2c1C(=O)C=C(N(C)C)C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.44
NQO1 P15559 1/20 0.36
POR P16435 1/20 0.36
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 3/20 0.33
CES1 P23141 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
RECQL P46063 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
THRB P10828 1/20 0.33
TXNRD1 Q16881 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18992075 0.74 MAPT (0.58) MALT1ALDH1A1MAPK1NPC1RAB9A
SCHEMBL13668567 0.74 ALDH1A1 (0.57) NQO1PORALDH1A1MAPK1CES1
SCHEMBL6152288 0.69 NQO1 (0.52) NQO1PORALDH1A1MAPK1CES1
SCHEMBL20191220 0.68 MAPT (0.46) MALT1ALDH1A1MAPK1CES1NPC1
SCHEMBL31290264 0.68 MALT1 (0.44) MALT1NQO1PORALDH1A1MAPK1
SCHEMBL8581251 0.68 IDO1 (0.48) ALDH1A1MAPK1KDM4EMEN1MAPT
SCHEMBL10446230 0.67 MALT1 (0.50) MALT1ALDH1A1CES1MEN1KMT2A
SCHEMBL8958289 0.67 MALT1 (0.50) MALT1ALDH1A1CES1PTPN1TSHR
SCHEMBL30029972 0.67 CDC25B (0.48) NQO1PORALDH1A1MAPK1NPC1
SCHEMBL14253089 0.67 CDC25B (0.48) NQO1PORALDH1A1MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118932351-A Electrochemical tandem preparation and application of antibacterial compound 2-amino quinone 温州医科大学附属口腔医院 2024-11-12 CN disclosed