Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.57 |
| ▸ | MTOR | P42345 | 7/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290160 | 0.90 | PIK3CA (0.57) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31290119 | 0.86 | PIK3CA (0.58) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31290140 | 0.82 | PIK3CA (0.53) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL4446943 | 0.81 | PIK3CA (0.64) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31290042 | 0.80 | PIK3CA (0.68) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31290230 | 0.80 | PIK3CA (0.60) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL4437336 | 0.79 | PIK3CA (0.69) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31290095 | 0.79 | PIK3CA (0.59) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL31290045 | 0.78 | HDAC1 (0.58) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL4438405 | 0.78 | PIK3CA (0.58) | PIK3CAMTORPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161359-A | Novel 4-morpholinyl thieno [3,2-d ] pyrimidine compound containing acrylamide structure and application thereof | 辽宁大学 | 2024-12-20 | — | — | CN | disclosed |