Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 17/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.60 |
| ▸ | MTOR | P42345 | 5/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290078 | 0.88 | PIK3CA (0.52) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL31290128 | 0.83 | ABCC4 (0.67) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL31290195 | 0.80 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL31290160 | 0.79 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL31290140 | 0.79 | PIK3CA (0.53) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL4439039 | 0.77 | PIK3CA (0.68) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL4440819 | 0.77 | PIK3CA (0.71) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL1181617 | 0.76 | PIK3CA (0.72) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL1181054 | 0.76 | PIK3CA (0.73) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL1180968 | 0.76 | PIK3CA (1.00) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161359-A | Novel 4-morpholinyl thieno [3,2-d ] pyrimidine compound containing acrylamide structure and application thereof | 辽宁大学 | 2024-12-20 | — | — | CN | disclosed |