Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 7/20 | 0.33 |
| ▸ | CCND1 | P24385 | 7/20 | 0.33 |
| ▸ | CCND2 | P30279 | 6/20 | 0.33 |
| ▸ | CCND3 | P30281 | 6/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885834 | 1.00 | WEE1 (0.35) | WEE1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL4826130 | 0.79 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CCNA2 | |
| SCHEMBL29507845 | 0.79 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CCNA2 | |
| SCHEMBL22171265 | 0.77 | CDK4 (0.32) | CDK4CCND1CCND2CCND3CCNA2 | |
| SCHEMBL30078181 | 0.77 | WEE1 (0.45) | WEE1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL24885507 | 0.77 | WEE1 (0.45) | WEE1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL22585647 | 0.76 | CDK4 (0.39) | CDK4CCND1CCND2CCND3CCNA2 | |
| SCHEMBL31290960 | 0.75 | WEE1 (0.34) | WEE1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL24885529 | 0.75 | WEE1 (0.34) | WEE1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL30878929 | 0.75 | USP19 (0.31) | PIM1TTKPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | MAP3K20, PRKCE, PRKCH | WEE1 649/4885MEN1 3726/4885KMT2A 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.