Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 3/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885518 | 1.00 | BRAF (0.47) | BRAFMAP4K4HCKBTKKDR | |
| SCHEMBL24885915 | 0.87 | BRAF (0.55) | BRAFMAP4K4HCKBTKKDR | |
| SCHEMBL2855636 | 0.85 | BRAF (0.54) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL2453008 | 0.81 | BRAF (0.69) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL15946928 | 0.73 | BRAF (0.67) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL2856446 | 0.72 | DYRK1A (0.46) | BRAFNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2858936 | 0.72 | DYRK1A (0.46) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL14705755 | 0.72 | BRAF (0.54) | BRAFMAP4K4HCKBTKKDR | |
| SCHEMBL14243031 | 0.72 | LCK (0.41) | HCKBTKGCKLDHAMAPT | |
| SCHEMBL2851409 | 0.70 | BRAF (0.62) | BRAFKDRPDGFRBKITFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | MAP3K20, PRKCE, PRKCH | BRAF 141/4885MAP4K4 64/4885HCK 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.