Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | HCK | P08631 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 10/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 9/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885518 | 0.87 | BRAF (0.47) | BRAFKDRHCKBTKMAP4K4 | |
| SCHEMBL31290967 | 0.87 | BRAF (0.47) | BRAFKDRHCKBTKMAP4K4 | |
| SCHEMBL2851409 | 0.78 | BRAF (0.62) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885740 | 0.74 | BRAF (0.47) | BRAFKDRHCKBTKPDGFRB | |
| SCHEMBL24886013 | 0.74 | BRAF (0.47) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL2851381 | 0.74 | BRAF (0.77) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL24885912 | 0.73 | BRAF (0.46) | BRAFKDRHCKBTKPDGFRB | |
| SCHEMBL2855636 | 0.73 | BRAF (0.54) | BRAFKDRPDGFRBKITFLT1 | |
| SCHEMBL14243031 | 0.72 | LCK (0.41) | HCKBTK | |
| SCHEMBL2861678 | 0.71 | BRAF (0.53) | BRAFKDRMAP4K4PDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |