Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 6/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18150738 | 0.91 | AOC3 (0.43) | TNFAOC3KCNH2MTOR | |
| SCHEMBL18150795 | 0.91 | AOC3 (0.43) | TNFAOC3KCNH2MTOR | |
| SCHEMBL18151375 | 0.91 | AOC3 (0.43) | TNFAOC3KCNH2MTOR | |
| SCHEMBL18153272 | 0.90 | AOC3 (0.36) | TNFAOC3BRD4RIPK1KCNH2 | |
| SCHEMBL18151071 | 0.90 | AOC3 (0.36) | TNFAOC3BRD4RIPK1KCNH2 | |
| SCHEMBL18153352 | 0.89 | TNF (0.35) | TNFAOC3BRD4CCNCCDK8 | |
| SCHEMBL18153231 | 0.88 | TNF (0.37) | TNFAOC3CCNCCDK8HDAC6 | |
| SCHEMBL18151037 | 0.88 | TNF (0.37) | TNFAOC3CCNCCDK8HDAC6 | |
| SCHEMBL18150884 | 0.88 | TNF (0.37) | TNFAOC3CCNCCDK8HDAC6 | |
| SCHEMBL18150926 | 0.88 | ABL1 (0.34) | TNFAOC3BRD4RIPK1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212727-A | Targeted bifunctional degradants | 耶鲁大学 | 2024-12-27 | — | — | CN | disclosed |