Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129248 | 1.00 | HTT (0.55) | HTTGAASMN1; SMN2PTGER1PTGER4 | |
| SCHEMBL3126052 | 0.87 | NFE2L2 (0.45) | HTTGAASMN1; SMN2NFE2L2TFEB | |
| SCHEMBL3126050 | 0.87 | NFE2L2 (0.45) | HTTGAASMN1; SMN2NFE2L2TFEB | |
| SCHEMBL3129598 | 0.86 | NFE2L2 (0.44) | HTTGAASMN1; SMN2NFE2L2TFEB | |
| SCHEMBL3129600 | 0.86 | NFE2L2 (0.44) | HTTGAASMN1; SMN2NFE2L2TFEB | |
| SCHEMBL22032605 | 0.85 | KDM4E (0.46) | HTTGAASMN1; SMN2MAPTLMNA | |
| SCHEMBL690962 | 0.84 | HTT (0.61) | HTTGAASMN1; SMN2PTGER1PTGER4 | |
| SCHEMBL3606823 | 0.83 | NFE2L2 (0.47) | HTTGAASMN1; SMN2PTGER1PTGER4 | |
| SCHEMBL3606819 | 0.83 | NFE2L2 (0.47) | HTTGAASMN1; SMN2PTGER1PTGER4 | |
| SCHEMBL3605646 | 0.79 | NFE2L2 (0.51) | NFE2L2TFEBMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209639-B1 | COMPOUNDS AS ANTI-MALARIALS AND THEIR PROCESS OF PREPARATION | COUNCIL SCIENT IND RES (IN) | 2020-09-16 | — | — | EP | disclosed |
| EP-3209639-B1 | COMPOUNDS AS ANTI-MALARIALS AND THEIR PROCESS OF PREPARATION | COUNCIL SCIENT IND RES (IN) | 2020-09-16 | — | — | EP | disclosed |
| US-20190106380-A1 | Aromatic Derivatives As Anti-Malarial | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-04-11 | — | — | US | disclosed |
| US-20190106380-A1 | Aromatic Derivatives As Anti-Malarial | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-04-11 | — | — | US | disclosed |
| EP-3209639-A2 | ANTI-MALARIAL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2017-08-30 | — | — | EP | disclosed |
| EP-0936211-B1 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | GIVAUDAN SA (CH) | 2010-07-07 | — | — | EP | disclosed |
| US-6956013-B2 | Photo-activated pro-fragrances | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-18 | — | — | US | disclosed |
| US-20040087454-A1 | Photo-activated pro-fragrances | PROCTER & GAMBLE COMPANY, THE | 2004-05-06 | — | — | US | disclosed |
| EP-1377538-A1 | PHOTO-ACTIVATED PRO-FRAGRANCES | THE PROCTER & GAMBLE COMPANY (US) | 2004-01-07 | — | — | EP | disclosed |
| US-20030004072-A1 | Photo-activated pro-fragrances | THE PROCTER & GAMBLE COMPANY | 2003-01-02 | — | — | US | disclosed |
| WO-2002083620-A1 | PHOTO-ACTIVATED PRO-FRAGRANCES | THE PROCTER & GAMBLE COMPANY (US) | 2002-10-24 | — | — | WO | disclosed |
| US-6096918-A | USEFUL FOR THE DELIVERY OF ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES, MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS. THEY CAN ALSO DELIVER FLUORESCENT WHITENING AGENTS. | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2000-08-01 | — | — | US | disclosed |
| EP-0936211-A2 | Aryl-acrylic acid esters useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106380-A1 | Aromatic Derivatives As Anti-Malarial | TYR, CYP3A43, H1-3 | HTT 917/4885GAA 1462/4885SMN1; SMN2 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.