Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130160 | 0.83 | TACR1 (0.44) | CARM1PRMT6OPRL1BCHEACHE | |
| SCHEMBL374621 | 0.83 | MAP4K4 (0.46) | CARM1PRMT6OPRL1BCHEACHE | |
| SCHEMBL5274750 | 0.80 | CARM1 (0.47) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL2095701 | 0.77 | MAP4K4 (0.38) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL18640401 | 0.77 | CARM1 (0.56) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL737354 | 0.74 | MAP4K4 (0.47) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL21902398 | 0.73 | CARM1 (0.48) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL21951131 | 0.73 | CARM1 (0.42) | CARM1PRMT6BCHEACHEBACE1 | |
| Formic Acid SCHEMBL5676546 | 0.72 | TEAD1 (0.46) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL28469040 | 0.71 | ALDH1A1 (0.51) | CARM1PRMT6MAP4K4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |