Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768653 | 0.87 | DHODH (0.40) | HSD17B10ME2ME1ME3DHODH | |
| SCHEMBL3129286 | 0.80 | KMT2A (0.51) | HSD17B10ME2ME1ME3DHODH | |
| SCHEMBL1079659 | 0.79 | HSD17B10 (0.45) | HSD17B10ME2ME1ME3DHODH | |
| SCHEMBL29195550 | 0.75 | MAPT (0.41) | HSD17B10FOLH1MAPTHDAC8PTGER4 | |
| SCHEMBL17961587 | 0.75 | FOLH1 (0.43) | HSD17B10MEN1KMT2AFOLH1MAPT | |
| SCHEMBL27736164 | 0.75 | MAPT (0.47) | HSD17B10NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL6904305 | 0.74 | ALDH1A1 (0.34) | HSD17B10DHODHMEN1KMT2AMAPT | |
| SCHEMBL2815958 | 0.74 | HSD17B10 (0.42) | HSD17B10ME2ME1ME3NR4A1 | |
| SCHEMBL9682139 | 0.74 | BID (0.44) | HSD17B10MAPT | |
| Trimethylammonium SCHEMBL28124204 | 0.73 | FOLH1 (0.41) | HSD17B10MEN1KMT2AFOLH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801159-B1 | A polytrimethylene naphthalate and method of making the same | FUTURA POLYESTERS LTD (IN) | 2010-07-21 | — | — | EP | disclosed |
| US-20070149756-A1 | Compositions and methods of manufacturing polytrimethylene naphthalate | FUTURA POLYESTERS LIMITED | 2007-06-28 | — | — | US | disclosed |
| EP-1801159-A1 | A polytrimethylene naphthalate and method of making the same | Futura Polyesters Limited (IN) | 2007-06-27 | — | — | EP | disclosed |