SCHEMBL312929

SCHEMBL312929

FC(F)(F)c1cccc(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 4/20 0.52
NOTUM Q6P988 2/20 0.44
TSHR P16473 2/20 0.42
HSD11B1 P28845 1/20 0.41
TYK2 P29597 1/20 0.40
PNMT P11086 1/20 0.39
CTSS P25774 2/20 0.39
CNR2 P34972 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
CTSK P43235 1/20 0.37
PTGS2 P35354 1/20 0.37
PDK2 Q15119 1/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764291 1.00 P2RX7 (0.52) P2RX7NOTUMTSHRHSD11B1TYK2
SCHEMBL1043059 0.87 P2RX7 (0.57) P2RX7NOTUMCTSSCTSKPDK2
SCHEMBL8665946 0.83 TSHR (0.41) P2RX7NOTUMTSHRHSD11B1TYK2
SCHEMBL10893212 0.83 P2RX7 (0.50) P2RX7NOTUMHSD11B1TYK2CTSS
SCHEMBL2013508 0.81 P2RX7 (0.41) P2RX7TSHRHSD11B1TYK2PTGS2
SCHEMBL4250305 0.81 NOTUM (0.50) P2RX7NOTUMHSD11B1CTSSCNR2
SCHEMBL9766677 0.79 TSHR (0.38) P2RX7NOTUMTSHRPNMTCYP1A2
SCHEMBL29467226 0.79 KCNN4 (0.48) P2RX7TSHRHSD11B1TYK2PTGS2
SCHEMBL5966718 0.79 KCNN4 (0.48) P2RX7TSHRHSD11B1TYK2PTGS2
SCHEMBL2262591 0.79 TSHR (0.46) TSHRPNMTCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306658-B Preparation method of chloropyridine and derivative thereof 内蒙古中辉生物科技有限公司 2025-05-09 CN claimed
CN-119306658-A Preparation method of chloropyridine and derivative thereof 内蒙古中辉生物科技有限公司 2025-01-14 CN claimed
CN-118672021-A Color microcup type electrophoresis electronic paper and processing method thereof 江汉大学 2024-09-20 CN claimed
CN-114289062-B Alkaline synthesized aluminum phosphate molecular sieve alkylation catalyst and application thereof 浙江恒逸石化研究院有限公司 2024-05-14 CN claimed
CN-117105809-B Benzanilide compound and preparation method and application thereof 中国农业大学 2024-05-03 CN claimed
CN-117865771-A Synthesis method of 2, 3-dichloro benzotrifluoride 上海泰初化工技术有限公司 2024-04-12 CN claimed
CN-117820180-A Sulfonyl trifluoro toluene compound 上海泰初化工技术有限公司 2024-04-05 CN claimed
CN-117105809-A Benzanilide compound and preparation method and application thereof 中国农业大学 2023-11-24 CN claimed
CN-117039172-A Lithium fluorocarboxylate sodium salt electrolyte 广东佳信新材料科技有限公司 2023-11-10 CN claimed
CN-113620867-B Synthesis method of fluopyram 内蒙古蓝科生物科技有限公司 2023-06-16 CN claimed
EP-1109771-A1 METHOD OF REDUCING RING CHLORINATION IN THE MANUFACTURE OF A TRICHLOROMETHOXYBENZENE OCCIDENTAL CHEMICAL CORPORATION, Occidental Tower (US) 2001-06-27 EP claimed
WO-2001005933-A1 CLEANING COMPOSITIONS LOCTITE CORPORATION (US) 2001-01-25 WO claimed
EP-1000010-A1 NITRATION PROCESS FOR DIPHENYL ETHERS ZENECA LIMITED (GB) 2000-05-17 EP claimed
WO-2000018984-A1 MULTI-COMPONENT SOLVENT SYSTEMS FOR FLUORINATED COMPOUNDS AND CLEANERS AND DELIVERY SYSTEMS BASED THEREON LOCTITE CORPORATION (US) 2000-04-06 WO claimed
WO-2000012456-A1 METHOD OF REDUCING RING CHLORINATION IN THE MANUFACTURE OF A TRICHLOROMETHOXYBENZENE OCCIDENTAL CHEMICAL CORPORATION (US) 2000-03-09 WO claimed
US-5959960-A Method of providing a range of conformalities for optical recording layers EASTMAN KODAK COMPANY (US) 1999-09-28 US claimed
WO-1999005087-A1 NITRATION PROCESS FOR DIPHENYL ETHERS ZENECA LIMITED (GB) 1999-02-04 WO claimed
EP-0860416-A1 Method of making trichloromethoxybenzene Occidental Chemical Corporation (US) 1998-08-26 EP claimed
US-5773668-A Method of making trichloromethoxybenzene OCCIDENTAL CHEMICAL CORPORATION (US) 1998-06-30 US claimed
EP-0833316-A2 A method of providing a range of conformalities for optical recording layers EASTMAN KODAK COMPANY (US) 1998-04-01 EP claimed