Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.54 |
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422319 | 1.00 | HTR2A (0.54) | HTR2ATRPM8MPOSLC6A4MAPT | |
| SCHEMBL13779243 | 0.83 | HTR2A (0.61) | HTR2ATRPM8MPOSLC6A4MAPT | |
| Hydrochloric Acid SCHEMBL21546049 | 0.81 | MPO (0.55) | HTR2ATRPM8MPOSLC6A4MAPT | |
| SCHEMBL25424612 | 0.75 | HTR2A (0.48) | HTR2ATRPM8MPOSLC6A4MAPT | |
| SCHEMBL19911038 | 0.73 | TNF (0.58) | HTR2AMPOSLC6A4MAPTNPSR1 | |
| SCHEMBL21315697 | 0.73 | TNF (0.58) | HTR2AMPOSLC6A4MAPTNPSR1 | |
| SCHEMBL7822537 | 0.71 | HTR2A (0.58) | HTR2ATRPM8MPOSLC6A4MAPT | |
| SCHEMBL20258550 | 0.71 | HTR2A (0.58) | HTR2ATRPM8MPOSLC6A4MAPT | |
| SCHEMBL30724496 | 0.70 | HTR2A (1.00) | HTR2ATRPM8MPOSLC6A4MAPT | |
| SCHEMBL626030 | 0.70 | HTR2A (1.00) | HTR2ATRPM8MPOSLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731623-A1 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC Therapeutics, Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025006078-A1 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |