Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.37 |
| ▸ | UBE2M | P61081 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293889 | 0.95 | POLB (0.48) | POLBRAB9ATP53EPHX2DCUN1D1 | |
| SCHEMBL31293891 | 0.89 | POLB (0.42) | POLBRAB9ATP53EPHX2DCUN1D1 | |
| SCHEMBL31293815 | 0.89 | DCUN1D1 (0.45) | DCUN1D1UBE2MCXCR3 | |
| SCHEMBL31293793 | 0.89 | POLB (0.41) | POLBRAB9ATP53EPHX2DCUN1D1 | |
| SCHEMBL31293791 | 0.87 | DCUN1D1 (0.42) | DCUN1D1UBE2MCXCR3 | |
| SCHEMBL31293689 | 0.86 | POLB (0.36) | POLBRAB9ACXCR3USP2CYP3A4 | |
| SCHEMBL31293761 | 0.86 | DCUN1D1 (0.48) | DCUN1D1UBE2M | |
| SCHEMBL31294038 | 0.86 | DCUN1D1 (0.51) | DCUN1D1UBE2M | |
| SCHEMBL31293852 | 0.86 | POLB (0.47) | POLBRAB9ATP53EPHX2DCUN1D1 | |
| SCHEMBL31293850 | 0.86 | POLB (0.45) | POLBRAB9ATP53EPHX2DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |