SCHEMBL31293791

SCHEMBL31293791

Cn1ccn2ncc(C(=O)N3CC4(CC(N(CC(F)(F)F)C(=O)Nc5cccc(C(F)(F)F)c5)C4)C3)c12

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 19/20 0.42
UBE2M P61081 17/20 0.42
CXCR3 P49682 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293815 0.94 DCUN1D1 (0.45) DCUN1D1UBE2MCXCR3
SCHEMBL31293761 0.91 DCUN1D1 (0.48) DCUN1D1UBE2M
SCHEMBL31294038 0.91 DCUN1D1 (0.51) DCUN1D1UBE2M
SCHEMBL31293889 0.89 POLB (0.48) DCUN1D1UBE2MCXCR3
SCHEMBL31293793 0.88 POLB (0.41) DCUN1D1UBE2M
SCHEMBL31293652 0.87 POLB (0.42) DCUN1D1UBE2MCXCR3
SCHEMBL31293661 0.85 LMNA (0.42)
SCHEMBL31293891 0.84 POLB (0.42) DCUN1D1UBE2MCXCR3
SCHEMBL31293845 0.84 EPHX2 (0.48) DCUN1D1UBE2M
SCHEMBL31294037 0.83 UBE2M (0.41) DCUN1D1UBE2M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP claimed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO claimed