Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.30 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293685 | 0.90 | POLB (0.47) | POLBRAB9ANPC1 | |
| SCHEMBL31293607 | 0.90 | USP2 (0.34) | POLBRAB9A | |
| SCHEMBL31293971 | 0.89 | EPHX2 (0.32) | USP30 | |
| SCHEMBL31293811 | 0.88 | POLB (0.33) | POLBRAB9A | |
| SCHEMBL31293407 | 0.87 | SYK (0.31) | — | |
| SCHEMBL31294007 | 0.86 | SPR (0.32) | — | |
| SCHEMBL31293851 | 0.85 | SCN10A (0.35) | SCN10AMALT1BIRC3 | |
| SCHEMBL31293734 | 0.85 | POLB (0.35) | POLBRAB9ASCN10AMALT1USP30 | |
| SCHEMBL31293966 | 0.85 | POLB (0.35) | POLBRAB9ASCN10AMALT1USP30 | |
| SCHEMBL31293545 | 0.84 | SYK (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |