Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 14/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 13/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 13/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 7/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570156 | 0.85 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL26685004 | 0.85 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31294103 | 0.81 | PBRM1 (0.40) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL30632466 | 0.80 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31293622 | 0.80 | SMARCA2 (0.53) | PBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL31570161 | 0.78 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL26684891 | 0.78 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31294027 | 0.78 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL21673834 | 0.77 | PBRM1 (0.67) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31582724 | 0.76 | SMARCA2 (0.40) | PBRM1SMARCA2SMARCA4NR1I2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709726-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233717-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-11-14 | — | — | WO | disclosed |