Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 4/20 | 0.53 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 4/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632526 | 0.82 | SMARCA2 (0.50) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL26685126 | 0.82 | SMARCA2 (0.50) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL31293862 | 0.82 | OXTR (0.40) | CYP11B2PARP1KRASEGLN2OXTR | |
| SCHEMBL30666247 | 0.80 | SMARCA2 (0.52) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL26683498 | 0.80 | SMARCA2 (0.52) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL31293952 | 0.80 | PBRM1 (0.41) | SMARCA2SMARCA4PBRM1NR1I2 | |
| SCHEMBL29619441 | 0.79 | SMARCA2 (0.53) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL30632451 | 0.76 | SMARCA2 (0.43) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL26685144 | 0.76 | SMARCA2 (0.43) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL30666283 | 0.76 | SMARCA2 (0.50) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709726-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233717-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-11-14 | — | — | WO | disclosed |