Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460281 | 0.90 | MAOB (0.60) | GPR35MAOAMAOBHPGDALDH1A1 | |
| SCHEMBL4382617 | 0.89 | GRIN1 (0.62) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL4382614 | 0.89 | GRIN1 (0.62) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL4382686 | 0.87 | HSP90AA1 (0.53) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL4382687 | 0.87 | HSP90AA1 (0.53) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL1366493 | 0.84 | MAOA (0.57) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL1367343 | 0.84 | MAOA (0.57) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL1366495 | 0.84 | MAOA (0.57) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL1368322 | 0.81 | MAOA (0.76) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL1367749 | 0.81 | MAOA (0.76) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12172985-B1 | 6-(6-bromo-2-oxo-2H-chromen-3-yl)-4-(3-bromophenyl)-2-alkoxynicotinonitrile as antimicrobial compounds | King Faisal University (SA) | 2024-12-24 | — | — | US | claimed |
| US-12172985-B1 | 6-(6-bromo-2-oxo-2H-chromen-3-yl)-4-(3-bromophenyl)-2-alkoxynicotinonitrile as antimicrobial compounds | King Faisal University (SA) | 2024-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12172985-B1 | 6-(6-bromo-2-oxo-2H-chromen-3-yl)-4-(3-bromophenyl)-2-alkoxynicotinonitrile as antimicrobial compounds | PNN, BECN1, NCL | GRIN1 3233/4885GRIN2A 3210/4885GRIN2B 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.